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ATP5O — HSPG2
Text-mined interactions from Literome
Banday et al., American journal of physiology. Renal physiology 2007
(Obesity) :
Lean and obese rats were given normal diet or diet supplemented with antioxidant lipoic acid for 2 wk. Compared with lean rats, obese rats exhibited oxidative stress, D1R were uncoupled from G ( q/11 ) alpha at basal level, and SKF-38393 failed to elicit D1R-G protein coupling, stimulate
phospholipase C (PLC) , and
inhibit Na-K-ATPase activity ... GRK2 interacts with G ( q/11 ) alpha and acts, at least in part, as a regulator of G protein signaling leading to the D1R-G ( q/11 ) alpha uncoupling, causing inability of SKF-38393 to stimulate
PLC and
inhibit Na/K-ATPase
Lin et al., Endocrinology 2010
(Calcium Signaling) :
Furthermore, the specific inhibition of MyH9
ATPase activity with Blebbistatin dose-dependently
suppressed FSH induced G alpha
h/PLC-delta 1 signaling and Ca ( 2+ ) -influx, but not intracellular cAMP accumulation in rat SCs, implying that MyH9 mediates FSH induced activation of G alpha h/PLC-delta 1/IP ( 3 ) /Ca ( 2+ ) -influx pathway in rat SCs
Suzuki et al., J Mol Cell Cardiol 1993
:
In order to understand interactions between oxidants and non-antioxidants, relationships between the
effects of superoxide anion radical ( O2- ) and
palmitoyl-L-carnitine (PLC) on the Ca ( 2+ )
-ATPase of vascular smooth muscle sarcoplasmic reticulum were studied ... These results demonstrate that O2- can inhibit stimulatory
effects of
PLC on the Ca ( 2+ )
-ATPase , however, PLC does not block the inhibitory effect of O2-