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TSHR — TTF1

Text-mined interactions from Literome

Fenton et al., Ann Clin Lab Sci 2001 (Disease Progression...) : Because thyrotropin ( TSH ) upregulates these same genes, we hypothesized TSH-R activation might increase TTF-1 and that TTF-1 might be differentially expressed in benign and malignant thyroid disease
Bhattacharyya et al., Thyroid 2005 : In order to determine whether TTF-1 might be involved in orbital TSHR expression, we used quantitative real-time polymerase chain reaction ( PCR ) to assess relative expression of this and other thyroid associated transcription factors ( TTF-2 and Pax-8 ) in GO orbital tissue specimens ( n = 28 ) and cultures ( n = 3 ), and in normal orbital tissues ( n = 19 ) and cultures ( n = 3 )
Shimura et al., Mol Endocrinol 1995 : Transfection experiments indicate that full, constitutive TSHR gene expression in FRTL-5 thyroid cells requires the binding of both SSBPs and TTF-1 , since mutation of either element halves thyroid-specific promoter activity, whereas mutation of both decreases promoter activity to values near those of a control vector ... In sum, full, constitutive expression of the TSHR in thyroid cells requires TTF-1 and the SSBPs to bind separate, contiguous elements on the TSHR promoter
Schuppert et al., Thyroid 1996 (Goiter...) : This increase of TSH-R expression levels is not due to an ongoing transcriptional activation of the TTF-1 gene