Gene interactions and pathways from curated databases and text-mining

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CD46 — NOX4

Text-mined interactions from Literome

Katsume et al., Arterioscler Thromb Vasc Biol 2011 (Aortic Diseases...) : Lysophosphatidylcholine activated PYK2 induced NADPH oxidase mediated ROS generation and ROS mediated synthesis of tumor necrosis factor-a (TNFa), vascular cell adhesion molecule-1 ( VCAM-1 ), monocyte chemotactic protein-1 (MCP-1) , and p21Cip1/Ets-1
Madeira et al., Eur J Pharmacol 2012 (Inflammation...) : L ( 3 ) Co had no effect on secretion of monocyte chemotactic protein-1 (MCP-1) by THP-1 cells, but it inhibited the NADPH oxidase dependent respiratory burst activity of differentiated human HL-60 cells