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CAV3 — SRC

Text-mined interactions from Literome

Minshall et al., Histochem Cell Biol 2002 : The Src induced phosphorylation of caveolin-1 is crucial in regulating interactions of caveolin-1 with other components of the signaling machinery such as G ( i ), and key signaling entry of caveolae into the cytoplasm and endocytosis of albumin and other solutes
Shajahan et al., J Biol Chem 2004 (Second Messenger Systems) : Expression of ct-betaARK also prevented Src mediated tyrosine phosphorylation of caveolin-1 and dynamin-2 and the resultant phosphorylation dependent association of dynamin-2 and caveolin-1
Podar et al., Cancer Res 2004 (Multiple Myeloma) : In the present study, we demonstrate that vascular endothelial growth factor ( VEGF ) triggers Src dependent phosphorylation of caveolin-1 , which is required for p130 ( Cas ) phosphorylation and multiple myeloma cell migration
Liu et al., Kidney Int 2005 : Depletion of caveolin-1 also significantly reduced the ouabain induced accumulation of Na/K-ATPase alpha-1 subunit, EGFR, Src , and MAPKs in clathrin-coat vesicles, as well as early and late endosomes
Galvagni et al., Biochemistry 2007 : Cell treatment with Src or Abl inhibitors PP2 or STI571, prior to receptor stimulation, affects caveolin-1 phosphorylation without affecting receptor autophosphorylation, suggesting that both Src and Abl are involved in VEGFR-3 dependent caveolin-1 phosphorylation
Head et al., FASEB J 2008 (Brain Ischemia) : Adenovirally mediated expression of caveolin-1 in neurons from caveolin-1 ( -/- ) mice restored NMDA mediated enhancement of P-Src and P-ERK1/2, redistributed NMDAR2B to buoyant fractions, and enhanced NMDAR2B localization to membrane rafts ... We conclude that caveolin-1 , perhaps via its ability to scaffold key signaling components, is essential for NMDAR localization to neuronal membrane rafts, NMDAR/Src tyrosine kinase family/ERK signaling, and protection of neurons from ischemic injury and cell death
Tencer et al., Anticancer Res 2008 : Inhibitors of Src and the Mek1-Erk1/2 and p38 MAP kinase pathways also inhibit up-regulation of caveolin-1 by rosiglitazone ... Our findings indicate that up-regulation of caveolin-1 by rosiglitazone requires superoxide formation and the activation of Src , EGFR, and the Mek1-Erk1/2 and p38 MAP kinase pathways
Lee et al., Cell Mol Life Sci 2009 : Src and caveolin-1 phosphorylation was increased by galectin-1, and phospho-caveolin-1 was inhibited by PP2
Park et al., Am J Physiol Cell Physiol 2009 : In conclusion, these results demonstrated that EGF induced DNA synthesis and cell migration are mediated by caveolin-1 , which is activated by Src , FAK, PI3K/Akt, ERK, and MMP-2 signals in mouse ES cells
Hawkins et al., J Neurosci 2010 : These findings indicate that VEGF decreases P-glycoprotein activity via activation of flk-1 and Src, and suggest Src mediated phosphorylation of caveolin-1 may play a role in downregulation of P-glycoprotein activity
Place et al., Mol Pharmacol 2011 : Cooperative role of caveolin-1 and C-terminal Src kinase binding protein in C-terminal Src kinase mediated negative regulation of c-Src
Basu Roy et al., Int J Cancer 2013 (Cell Transformation, Neoplastic...) : However, caveolin-1 overexpression by itself does not increase migration whereas an activated Src can increase migration in a caveolin-1 dependent manner
Boscher et al., Mol Biol Cell 2013 (Breast Neoplasms...) : ILK, Src , and galectin-3 also mediate EGF stimulation of caveolin-1 phosphorylation ... Direct activation of integrin with Mn ( 2+ ) induces galectin-3, ILK, and Src dependent RhoA activation and caveolin-1 phosphorylation