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PTGS2 — SYT1

Text-mined interactions from Literome

Al-Ashy et al., Cytokine 2006 (Inflammation) : Inhibition of translocated p65 binding to DNA, inhibited COX-2 production and induced apoptosis
Basu et al., Cell Microbiol 2007 : Taken together, our results show that co-ordinated post-translational modifications of p65 and histone H3 involving phosphorylation and acetylation drive COX-2 dependent transcriptional activation of the MMP-9 gene in response to challenge of macrophages with M. avium
Polk et al., Am J Physiol Cell Physiol 2007 (Nephritis) : Moreover, inhibition of COX-2 activity results in persistent p65-DNA binding, IkappaBalpha phosphorylation, and IKKbeta activity, similar to that observed after prevention of RhoA/AP-1 axis signaling
Vaid et al., PloS one 2011 : Further, GSPs inhibited the activation of NF-?B/p65 , an upstream regulator of COX-2 , in melanoma cells, and treatment of cells with caffeic acid phenethyl ester, an inhibitor of NF-?B, also inhibited cell migration
Singh et al., PloS one 2011 (Melanoma...) : Moreover, EGCG inhibited the activation of NF-?B/p65 , an upstream regulator of COX-2 , in A375 melanoma cells, and treatment of cells with caffeic acid phenethyl ester, an inhibitor of NF-?B, also inhibited cell migration
Singh et al., PloS one 2013 (Carcinoma, Non-Small-Cell Lung...) : Honokiol inhibited PGE2 enhanced migration of NSCLC cells, inhibited the activation of NF-?B/p65 , an upstream regulator of COX-2 , in A549 and H1299 cells, and treatment of cells with caffeic acid phenethyl ester, an inhibitor of NF-?B, also inhibited migration of NSCLC cells