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ADCY2 — CDKN1A
Text-mined interactions from Literome
Prasad et al., J Am Coll Nutr 1999
(Neoplasms) :
The proposed mechanisms for these effects include inhibition of protein kinase C activity, prostaglandin E1-stimulated
adenylate cyclase activity, expression of c-myc, H-ras, and a transcription factor ( E2F ), and
induction of transforming growth factor-beta and
p21 genes
Konishi-Imamura et al., Biochem Biophys Res Commun 1988
(Cell Transformation, Neoplastic) :
It was considered that
p21 plays enhancing role in coupling of GTP binding proteins to
adenylate cyclase
Beckner et al., Nature 1985
(Cell Transformation, Neoplastic) :
We have therefore now examined the structural and functional similarities between p21 and Ns and Ni and find no evidence that
p21 regulates
adenylate cyclase activity by acting as one of these regulatory proteins