Gene interactions and pathways from curated databases and text-mining

◀ Back to PIK3R1

PIK3R1 — SLC2A1

Text-mined interactions from Literome

Barata et al., J Exp Med 2004 (Precursor Cell Lymphoblastic Leukemia-Lymphoma) : PI3K signaling was also required for cell size increase, up-regulation of CD71, expression of the glucose transporter Glut1 , uptake of glucose, and maintenance of mitochondrial integrity
Barata et al., Leukemia & lymphoma 2005 (Leukemia-Lymphoma, Adult T-Cell) : PI3K signaling is also required for the expression of the glucose transporter Glut1 , uptake of glucose, activation of the metabolic machinery, increase in cell size, and maintenance of mitochondrial integrity
Swainson et al., Blood 2007 : Glut-1 is directly regulated by PI3K and, indeed, inhibiting PI3K activity abrogates IL-7 induced proliferation
Shang et al., J Endocrinol 2008 : Rb(1) induced glucose uptake as well as GLUT1 and GLUT4 translocations was inhibited by the PI3K inhibitor
Melstrom et al., Pancreas 2008 (Pancreatic Neoplasms) : In addition, the inhibitory effects of apigenin and the PI3K inhibitors on GLUT-1 are similar, indicating that the PI3K/Akt pathway is involved in mediating apigenin 's effects on downstream targets such as GLUT-1