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NFKB1 — SLC22A3

Text-mined interactions from Literome

Huber et al., J Clin Invest 2004 (Breast Neoplasms...) : Inhibition of NF-kappaB signaling prevented EMT in Ras transformed epithelial cells, while activation of this pathway promoted the transition to a mesenchymal phenotype even in the absence of TGF-beta
Huber et al., Cell cycle (Georgetown, Tex.) 2004 : In a combined in vitro/in vivo model of mammary carcinogenesis, NF-kappaB was essential both for the induction and maintenance of EMT and for in vivo metastasis
Sarkar et al., Int Rev Immunol 2008 (Cell Transformation, Neoplastic...) : More importantly, recent studies have shown that NF-kappaB signaling also plays critical roles in the epithelial-mesenchymal transition (EMT) and cancer stem cells
Zhang et al., Clin Cancer Res 2009 (Neoplasm Recurrence, Local...) : In prostate cancer cell lines, TGF-beta induced EMT was mediated by NF-kappaB signaling ... The detection of NF-kappaB mediated TGF-beta induced EMT in primary tumors predicts disease recurrence in prostate cancer patients following radical prostatectomy
Pantuck et al., Cancer Res 2010 (Carcinoma, Renal Cell...) : Based on earlier evidence that VHL loss can activate NF-kappaB, a known mediator of EMT, we tested whether NF-kappaB contributed to VHL mediated effects on EMT