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IL12B — IL17D

Text-mined interactions from Literome

Lucas et al., Proc Natl Acad Sci U S A 2003 : IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1 dependent and -independent mechanisms
Rowland et al., Infect Immun 2006 (Glanders) : IL-12 was essential for IFN-gamma production in vitro ; IL-18 was also involved in induction of IFN-gamma, but IL-27 was not required for IFN-gamma production in response to heat killed B. mallei
Owaki et al., J Immunol 2006 : Finally, IL-12Rbeta2 expression was shown to be up-regulated by IL-27 in both T-bet- and ICAM-1/LFA-1 dependent mechanisms
Fitzgerald et al., J Immunol 2007 (Encephalomyelitis, Autoimmune, Experimental...) : IL-27 significantly inhibited both nonpolarized and IL-23-driven IL-17 production by myelin-reactive T cells thereby suppressing their encephalitogenicity in adoptive transfer EAE
Robinson et al., J Infect Dis 2008 (Tuberculosis) : Quantitative measurement of transcripts showed that IL-12 or M. tuberculosis induced IL-27 gene expression in human macrophages
Zhang et al., Clin Neurol Neurosurg 2010 (Autoimmune Diseases...) : IFNbeta inhibited IL-1beta, IL-23 and transforming growth factor ( TGF ) -beta ( which induce Th17 cell differentiation ), and induced IL-27 , IL-12p35 and IL-10 ( which suppress it ) in dendritic cells (DCs) and B-cells
Zeitvogel et al., Exp Dermatol 2012 : IL-27 acts as a priming signal for IL-23 but not IL-12 production on human antigen presenting cells ... IL-27 acts as a priming signal for IL-23 but not IL-12 production on human antigen presenting cells