Gene interactions and pathways from curated databases and text-mining

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IL4 — PTX3

Text-mined interactions from Literome

Fujimoto et al., Intern Med 1999 (Paraparesis, Tropical Spastic) : PTX treatment induced incremental increases in the levels of IL-4 and IL-10 in both sera and CSF of 6 HAM patients
Schneider et al., Infect Immun 2007 : Stimulation of T cells with holotoxin ( PTx ) or the B subunit alone ( PTxB ) rapidly induces signaling events resulting in inositol phosphate accumulation, Ca ( 2+ ) mobilization, interleukin-2 (IL-2) production, and mitogenic cell growth
Yamamoto et al., Hemodial Int 2013 (Cardiovascular Diseases...) : While C-reactive protein did not change, interleukin-6 (IL-6) increased by 14 % and pentraxin 3 (PTX3) increased by 45 %
Alles et al., Blood 1994 : IL-4 , but not dexamethasone or transforming growth factor-beta, inhibited PTX3 expression in monocytes
Dong et al., J Clin Immunol 1997 : PTX at a 3.5 x 10 ( -5 ) M concentration significantly inhibited T cell proliferation and the production of tumor necrosis factor-alpha, interleukin-2 , and interleukin-4 ... PTX at a 3.5 x 10 ( -5 ) M concentration significantly inhibited T cell proliferation and the production of tumor necrosis factor-alpha, interleukin-2, and interleukin-4
Schratzberger et al., Immunopharmacology 1999 : In the present study, we investigated the effects of the anti-inflammatory drug pentoxifylline ( PTX ) on activation of endothelial cells for enhanced adhesion and transmigration of neutrophils by lipopolysaccharide (LPS), tumor necrosis factor-alpha (TNF), interleukin-1 (IL-1) and granulocyte colony stimulating factor ( G-CSF )