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LIMS1 — PXN

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: Complex of ILK-LIMS1-PARVA-PXN (increases, ILK/LIMS1/PARVA/PXN Activity) Attwell et al., Mol Biol Cell 2003*
  Evidence: Interestingly, the interaction of CH-ILKBP with ILK is regulated by the Pi3 kinase pathway, because inhibition of Pi3 kinase activity by pharmacological inhibitors, or by the tumor suppressor PTEN, inhibits this interaction as well as cell attachment and signaling.
• OpenBEL Selventa BEL large corpus: GSK3B → Complex of ILK-LIMS1-PARVA-PXN (increases)
  Attwell et al., Mol Biol Cell 2003*
  Evidence: # Ariadne: Furthermore, CH-ILKBP stimulated GSK-3 beta phosphorylation on Ser 9, and phosphorylation of PKB/Akt on Ser 473, both of which have been shown previously to be regulated by ILK (Delcommenne et al., 1998 ). [Regulation]
• NCI Pathway Database Integrin-linked kinase signaling: ILK/PINCH1/alpha parvin complex (ILK-LIMS1-PARVA) → Paxillin (PXN) (modification, collaborate) Nikolopoulos et al., J Biol Chem 2002*
  Evidence: physical interaction
• NCI Pathway Database Integrin-linked kinase signaling: ILK/PINCH1/alpha parvin complex (ILK-LIMS1-PARVA) → ILK/PINCH1/alpha parvin/Paxillin complex (ILK-LIMS1-PARVA-PXN) (modification, collaborate)
  Nikolopoulos et al., J Biol Chem 2002*
  Evidence: physical interaction
• NCI Pathway Database Integrin-linked kinase signaling: Paxillin (PXN) → ILK/PINCH1/alpha parvin/Paxillin complex (ILK-LIMS1-PARVA-PXN) (modification, collaborate)
  Nikolopoulos et al., J Biol Chem 2002*
  Evidence: physical interaction