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HSPG2 — IL8

Text-mined interactions from Literome

Wu et al., Science 1993 : The pathways by which IL-8 activates inositide-specific phospholipase C (PLC) were investigated by co-expression of different components of the guanosine triphosphate binding protein ( G protein ) pathway in COS-7 cells
Bryant et al., Infect Immun 1996 : PLC strongly induced expression of ELAM-1, ICAM-1, and IL-8 , while PFO stimulated early ICAM-1 expression but did not promote ELAM-1 expression or IL-8 synthesis
König et al., J Med Microbiol 1997 (Hemolysis) : Purified PLC-H ( only at low concentrations up to 1 unit/4 x 10 ( 5 ) monocytes ), induced a dose dependent increase in IL-8 release and IL-8-specific mRNA expression over that of unstimulated cells ( at 4-, 12- and 24-h incubation times ) ... These results contribute to the understanding of the role of both P. aeruginosa PLC in IL-8 generation during their interaction with human monocytes
Tschaikowsky et al., J Pharmacol Exp Ther 1998 (Shock, Septic) : Inhibition of PC-PLC by the specific inhibitor tricyclodecan-9-yl-xanthogenate ( D609 ) before LPS reduced the release of interleukin-1 beta, interleukin-6 and nitric oxide ( NO ) in vivo