Kehlen et al., Cancer Res 2003
(Carcinoma...) :
In the undifferentiated thyroid carcinoma cell line 1736, APN/CD13 mRNA expression could be increased by epidermal growth factor, basic fibroblast growth factor, interleukin-6 , and tumor necrosis factor alpha
Kanayama et al., J Leukoc Biol 1995
:
These results suggest that the expression and release of IL-8 from phagocytic cells are regulated by the proteolytic effect of APN on IL-8