Gene interactions and pathways from curated databases and text-mining

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CNR1 — PPARA

Text-mined interactions from Literome

Du et al., Br J Pharmacol 2011 (Inflammation...) : Our results suggest that CB(1) receptor dependent PPAR? expression is an important and novel signalling pathway in endocannabinoid 2-AG produced resolution of neuroinflammation in response to pro-inflammatory insults
Fakhfouri et al., Neuropharmacology 2012 (Alzheimer Disease...) : Of great note, both direct and CB1 mediated increase in PPAR-? signaling also contributes to WIN induced neuroprotection
Citraro et al., Neuropharmacology 2013 (Epilepsy, Absence) : Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-a receptor activation in a genetic model of absence epilepsy