Gene interactions and pathways from curated databases and text-mining

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HDAC4 — MYLIP

Text-mined interactions from Literome

Winbanks et al., J Biol Chem 2011 : We confirmed that increased expression of miR-206 and miR-29 resulted in the translational repression of HDAC4 in the presence or absence of TGF-ß via interaction with the HDAC4 3'-untranslated region ... Furthermore, we present evidence that the mechanism by which miR-206 and miR-29 can inhibit the TGF-ß mediated up-regulation of HDAC4 is via the inhibition of Smad3 expression, a transducer of TGF-ß signaling
Yuan et al., Hepatology 2011 (Carcinoma, Hepatocellular...) : Furthermore, our results suggested that the histone deacetylase 4 (HDAC4) inhibited the expression of miR-200a and its promoter activity and reduced the histone H3 acetylation level at the mir-200a promoter through a Sp1 dependent pathway ... Interestingly, we observed that the miR-200a directly targeted the 3'-untranslated region of the HDAC4 messenger RNA and repressed expression of HDAC4
Lodrini et al., Nucleic Acids Res 2013 (Neuroblastoma) : In profiling studies, histone deacetylase (HDAC) inhibitor treatment most strongly induced miR-183