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CSNK1A1 — WNT1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Hagen et al., Biochem Biophys Res Commun 2002
:
Ser45 phosphorylation in intact cells is not mediated by
CK1varepsilon , a known positive
regulator of
Wnt signalling, as overexpression of this kinase leads to decreased phosphorylation levels
Casagolda et al., J Cell Sci 2010
:
A
p120-catenin-CK1epsilon complex
regulates Wnt signaling
Cruciat et al., Science 2013
(Wnt Signaling Pathway) :
Contrary to this notion, we have identified the DEAD-box RNA helicase DDX3 as a regulator of the Wnt-ß-catenin network, where it acts as a regulatory subunit of CK1e : In a
Wnt dependent manner, DDX3 binds
CK1e and directly stimulates its kinase activity, and promotes phosphorylation of the scaffold protein dishevelled