Gene interactions and pathways from curated databases and text-mining

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IL17A — PTGS2

Text-mined interactions from Literome

Zhang et al., J Gastroenterol Hepatol 2005 : These findings suggest that COX-2 expression and prostaglandin synthesis might be regulated by both T-cell derived factor ( IL-17 ) and bacterial products ( LPS ) in the inflamed mucosa
Kanda et al., J Allergy Clin Immunol 2005 : The stimulatory effects of IL-17 on COX-2 expression were suppressed by inhibitors of p38 mitogen activated protein kinase ( MAPK ) and extracellular signal regulated kinase ( ERK ) kinase
Zhang et al., Arch Oral Biol 2010 : The expression of COX-2 , IL-1alpha, IL-6, IL-8, IL-11, and TNF-alpha, as well as PGE ( 2 ) production increased in the presence of IL-17A , whereas COX-1 expression did not change ... Celecoxib blocked the stimulatory effect of IL-17A on the expression of COX-2 , IL-1alpha, IL-6, IL-8, and IL-11 as well as PGE ( 2 ) production, whereas it did not block TNF-alpha expression