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IL17A — PTGS2
Text-mined interactions from Literome
Zhang et al., J Gastroenterol Hepatol 2005
:
These findings suggest that
COX-2 expression and prostaglandin synthesis might be
regulated by both T-cell derived factor (
IL-17 ) and bacterial products ( LPS ) in the inflamed mucosa
Kanda et al., J Allergy Clin Immunol 2005
:
The stimulatory
effects of
IL-17 on
COX-2 expression were suppressed by inhibitors of p38 mitogen activated protein kinase ( MAPK ) and extracellular signal regulated kinase ( ERK ) kinase
Zhang et al., Arch Oral Biol 2010
:
The expression of
COX-2 , IL-1alpha, IL-6, IL-8, IL-11, and TNF-alpha, as well as PGE ( 2 ) production
increased in the presence of
IL-17A , whereas COX-1 expression did not change ... Celecoxib blocked the stimulatory
effect of
IL-17A on the expression of
COX-2 , IL-1alpha, IL-6, IL-8, and IL-11 as well as PGE ( 2 ) production, whereas it did not block TNF-alpha expression