Gu et al., EMBO J 1992
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Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15 Da Costa et al., Plant Cell 2006
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Phosphorylation of the conserved regulatory Tyr-15 is involved in the binding of CDK to PAS2
Poon et al., J Biol Chem 1996
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Taken together, these results suggest that different CDKs are inhibited by different mechanisms following UV-induced DNA damage : Cdk2 is inhibited by the elevated level of p21 ; Cdk4 is inhibited by cooperation of p21 with other CDK inhibitors, like p27, and possibly by phosphorylation ; and Cdc2 is inhibited by Thr-14/Tyr-15 phosphorylation