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ALK — BCL10
Text-mined interactions from Literome
Zamo et al., Oncogene 2002
(Lymphoma, Large-Cell, Anaplastic) :
NPM-ALK expression
caused enhanced
Bcl-x ( L ) transcription, largely mediated by Stat3
Coluccia et al., Blood 2004
(Lymphoma, Large B-Cell, Diffuse) :
In this report, the
NPM/ALK mediated induction of
Bcl-XL ( but not of Bcl-2 ) was identified in human ALCL derived cells ...
NPM/ALK kinase activity was
required to promote
Bcl-XL expression and its protective effect on mitochondrial homeostasis
Xu et al., Mol Cancer Res 2006
(Carcinoma...) :
ALK7-ca induced the expression of proapoptotic factor Bax but
suppressed the expression of antiapoptotic factors Bcl-2,
Bcl-XL , and Xiap