Gene interactions and pathways from curated databases and text-mining

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LIF — TP53

Text-mined interactions from Literome

Hu et al., Nature 2007 : p53 can regulate both basal and inducible transcription of LIF
Baxter et al., J Neurooncol 2010 (Medulloblastoma) : p53 Regulates LIF expression in human medulloblastoma cells ... We also used p53-/- and p53+/+ isogenic HCT116 colorectal carcinoma cell lines, already reported to exhibit p53 dependent expression of the LIF D transcript, to establish the extent of p53-dependency for LIF M and T alternative transcripts
Feng et al., FASEB J 2011 (Infertility, Female) : This article reports that p53 and estrogen receptor a were activated in endometrial tissues during implantation to coordinately regulate LIF production
Zhu et al., Yi Chuan 2012 (Infertility, Female) : p53 regulates the LIF ( leukaemia inhibitory factor ) expression level by its DBD domain, and thus contributes to female reproduction by affecting the embryo implantation process
Kamohara et al., Int J Cancer 1997 (Carcinoma...) : LIF induced apoptosis related genes c-myc and ICE during suppression of cell growth, but p53 , p21, c-fos, cyclin A and cyclin E were not induced