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TNFRSF17 — TNFSF13B

Pathways - manually collected, often from reviews:

• BioCarta yaci and bcma stimulation of b cell immune responses: BAFF/BCMA/TRAF6/TRAF5/TRAF3 complex (TNFRSF17-TRAF6-TRAF5-TRAF3-TNFSF13B) → BCMA/TRAF6/TRAF5/TRAF3 complex (TNFRSF17-TRAF6-TRAF5-TRAF3) (modification, collaborate)
  
• BioCarta yaci and bcma stimulation of b cell immune responses: BAFF/BCMA/TRAF6/TRAF5/TRAF3 complex (TNFRSF17-TRAF6-TRAF5-TRAF3-TNFSF13B) → BAFF (TNFSF13B) (modification, collaborate)
• BioCarta yaci and bcma stimulation of b cell immune responses: BCMA/TRAF6/TRAF5/TRAF3 complex (TNFRSF17-TRAF6-TRAF5-TRAF3) → BAFF (TNFSF13B) (modification, collaborate)
• KEGG Intestinal immune network for IgA production: TNFSF13B → TNFRSF17 (protein-protein, activation)
• KEGG Cytokine-cytokine receptor interaction: TNFSF13B → TNFRSF17 (protein-protein, activation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: TNFSF13B — TNFRSF17 (physical association, affinity chromatography technology) Shu et al., Proc Natl Acad Sci U S A 2000*
• IRef Biogrid Interaction: TNFSF13B — TNFRSF17 (association, x-ray crystallography) Liu et al., Nature 2003*
• IRef Hprd Interaction: TNFSF13B — TNFRSF17 (in vitro) Gross et al., Nature 2000*, Shu et al., Proc Natl Acad Sci U S A 2000*, Yu et al., Nat Immunol 2000*
• IRef Hprd Interaction: TNFSF13B — TNFRSF17 (in vivo) Gross et al., Nature 2000*, Shu et al., Proc Natl Acad Sci U S A 2000*, Yu et al., Nat Immunol 2000*
• IRef Intact Interaction: TNFSF13B — TNFRSF17 (physical association, saturation binding) Gross et al., Nature 2000*
• IRef Ophid Interaction: TNFSF13B — TNFRSF17 (aggregation, confirmational text mining) Yu et al., Nat Immunol 2000*
• IRef Ophid Interaction: TNFSF13B — TNFRSF17 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Chiu et al., Blood 2007 (Hodgkin Disease) : Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL
Koarada et al., Rheumatology (Oxford) 2010 (Lupus Erythematosus, Systemic) : RP105 ( - ) B cells from SLE patients showed more preferential expression of BCMA compared with BAFF-R than normal subjects, and were possibly regulated by BAFF/APRIL
Kim et al., J Leukoc Biol 2011 : Subsequent analysis of BAFF signaling suggested that BAFF induces AID through BCMA , a BAFF-receptor, and p38MAPK and CREB act as intermediates in AID expression