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BCL2 — CDH1
Text-mined interactions from Literome
Sasaki et al., Int J Cancer 2000
(Neoplasm Invasiveness) :
Therefore,
E-cadherin may negatively
regulate Bcl-2 expression by altering the availability of nuclear beta-catenin ... Loss of
E-cadherin in invasive tumor cells may
lead to increased
Bcl-2 expression and resistance to chemotherapeutic drugs
Li et al., J Cell Sci 2003
:
Overexpression of
Bcl-2 in estrogen receptor positive MCF-7 mammary carcinoma cells
led to decreased cell surface
E-cadherin and the disruption of junctional complexes concurrent with intracellular redistribution of their components
Du et al., PLoS Biol 2007
(Adenoma, Islet Cell...) :
Although no changes were observed in rates of proliferation or apoptosis,
Bcl-xL altered cell morphology, remodeled the actin cytoskeleton, and
down-regulated cadherin 1 ; it also induced cell migration and invasion, as evaluated using two-chamber transwell assays