◀ Back to CDKN1A
CDKN1A — RUNX1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Peterson et al., Blood 2007
(Leukemia...) :
Thus, loss of p21 ( WAF1 ) facilitates AML1-ETO induced leukemogenesis, suggesting that mutagenic events in the p21 ( WAF1 ) pathway to bypass the growth inhibitory effect from
AML1-ETO induced
p21 ( WAF1 ) expression can be a significant factor in AML1-ETO associated acute myeloid leukemia
Hasegawa et al., Cancer Sci 2007
(Biliary Tract Neoplasms) :
Based on these results,
RUNX3 is
involved in TGF-beta induced expression of
p21 and the resulting induction of TGF-beta dependent G ( 1 ) arrest
Lee et al., Proc Natl Acad Sci U S A 2013
:
Conversely, we find that
Runx1 ( runt related transcription factor 1 ), which is known for promoting HFSC proliferation,
represses p21 , p27, p57, and p15 transcription in HFSC in vivo