◀ Back to IL8
EPO — IL8
Text-mined interactions from Literome
Fandrey et al., Ann N Y Acad Sci 1991
(Carcinoma, Hepatocellular...) :
A dose dependent decrease of up to 60 % in
Epo production was
induced by interleukin-1 beta,
interleukin-1 alpha, and tumor necrosis factor-alpha ( in that order of potency )
Ghinassi et al., Exp Hematol 2007
:
These results suggest that interleukin-3 and erythropoietin cooperate to establish the lineage-specific transcription factor milieu of erythroid cells
: interleukin-3 regulates mainly gene transcription and
erythropoietin consistently
increases mRNA and protein stability
Lifshitz et al., Haematologica 2010
:
The macrophages derived in-vitro from bone marrow cells expressed erythropoietin receptor transcripts, and in-vitro stimulation with
erythropoietin activated multiple signaling pathways, including signal transducer and activator of transcription ( STAT ) 1 and 5, mitogen activated protein kinase, phosphatidylinositol 3-kinase and nuclear factor kappa B. In-vitro erythropoietin treatment of these cells up-regulated their surface expression of CD11b, F4/80 and CD80, enhanced their phagocytic activity and nitric oxide secretion, and also
led to augmented
interleukin 12 secretion and decreased interleukin 10 secretion in response to lipopolysaccharide