Lents et al., J Biol Chem 2002
:
Consistent with a role for ERK in Thr-160 phosphorylation, expression of constitutively active Raf-1 induces Thr-160 phosphorylation of CDK2-NLS in serum arrested cells, an effect that is blocked by treatment with U0126
Kerkhoff et al., Mol Cell Biol 1997
(Cell Transformation, Neoplastic) :
The activation of the c-Raf-1-BxB-ER protein leads to an accumulation of high levels of cyclin D1 protein and a repression of the p27Kip1 cyclin dependent kinase inhibitor under all culture conditions tested