Gene interactions and pathways from curated databases and text-mining

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BMP2 — EDN1

Text-mined interactions from Literome

Nett et al., Life Sci 2006 (Diabetes Mellitus, Experimental...) : Transcriptional regulation of vascular bone morphogenetic protein by endothelin receptors in early autoimmune diabetes mellitus
Alexander et al., Development 2011 : Inhibition of BMP signaling at these stages reduces expression of the ventral signal Edn1 , as well as ventral-specific genes such as hand2 and dlx6a in the arches, and expands expression of the dorsal signal jag1b ... Soon after NC migration, BMP is required to induce Edn1 and overexpression of either signal partially rescues ventral skeletal defects in embryos deficient for the other