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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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IL12A — IL17D

Text-mined interactions from Literome

Lucas et al., Proc Natl Acad Sci U S A 2003 : IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1 dependent and -independent mechanisms
Rowland et al., Infect Immun 2006 (Glanders) : IL-12 was essential for IFN-gamma production in vitro ; IL-18 was also involved in induction of IFN-gamma, but IL-27 was not required for IFN-gamma production in response to heat killed B. mallei
Owaki et al., J Immunol 2006 : Finally, IL-12Rbeta2 expression was shown to be up-regulated by IL-27 in both T-bet- and ICAM-1/LFA-1 dependent mechanisms
Robinson et al., J Infect Dis 2008 (Tuberculosis) : Quantitative measurement of transcripts showed that IL-12 or M. tuberculosis induced IL-27 gene expression in human macrophages
Zeitvogel et al., Exp Dermatol 2012 : IL-27 acts as a priming signal for IL-23 but not IL-12 production on human antigen presenting cells