Gene interactions and pathways from curated databases and text-mining

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MAP2K1 — PEA15

Text-mined interactions from Literome

Ramos et al., Mol Biol Cell 2000 : PEA-15 expression in Chinese hamster ovary cells resulted in an increased mitogen activated protein kinase kinase and ERK activity
Whitehurst et al., J Biol Chem 2004 (MAP Kinase Signaling System) : Consistent with its recognition of the MAP kinase insert, PEA-15 blocked activation of ERK2 by MEK1 , which also requires the MAP kinase insert to interact productively with ERK2