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TIPRL — TP53
Text-mined interactions from Literome
Shi et al., World J Gastroenterol 2005
(Carcinoma, Hepatocellular...) :
In comparison with HepG2 cells, these data suggested that
up-regulation of
p53 levels by
TIP30 might be a pre-requisite for Bax and Bax/Bcl-xl ratio increase
Zhao et al., Hepatology 2006
(Carcinoma, Hepatocellular...) :
Ectopic expression of
TIP30 in HCC cells
enhanced p53 expression and decreased Bcl-2/Bcl-xL expression
Lee et al., Mol Cells 2012
:
In addition to such a post-transcriptional mechanism via which
TIP30 increases the
p53 level, it has been proposed that TIP30 may regulate p53 protein at the protein level by directly binding to it