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HMGB1 — IL12B
Text-mined interactions from Literome
Dumitriu et al., J Immunol 2005
:
This secreted
HMGB1 is
necessary for the up-regulation of CD80, CD83, and CD86 surface markers of human dendritic cells and for
IL-12 production
Ivanov et al., Blood 2007
:
Loss of
HMGB1 leads to a defect in the IL-6,
IL-12 , TNFalpha, and iNOS response to CpG-ODN
Zhu et al., Transplantation 2013
(Disease Models, Animal...) :
Meanwhile,
Hmgb1 increased after IR injury and the Hmgb1 inhibitor glycyrrhizin markedly
reduced the production of
IL-23 and IL-17A and ameliorated myocardial IR injury