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ANXA6 — PDGFB

Text-mined interactions from Literome

Yellaturu et al., J Biol Chem 2002 : On the other hand, LY294002 and wortmannin, specific inhibitors of PI3K, prevented PDGF-BB induced phosphorylation of Akt and its downstream effector molecules, p70S6K , ribosomal protein S6, 4E-BP1, and eIF4E ... NEM also abrogated the phosphorylation of p70S6K , ribosomal protein S6, 4E-BP1, and eIF4E induced by PDGF-BB , suggesting that thiol alkylation interferes with the PI3K/Akt pathway at the level of Akt
Choi et al., Cardiovasc Res 2010 (MAP Kinase Signaling System) : Western blot analysis showed that PDGF-BB induced phosphorylation of Akt, p70S6K , and p38 was inhibited by piceatannol, but not resveratrol
Yao et al., J Neurosci 2012 : Blocking TRPC1 channel suppressed PDGF mediated proliferation as well as PDGF-BB induced ERK/CREB and mTOR/4E-BP-p70S6K activation, thereby underscoring its role in this process