Flint et al., Domest Anim Endocrinol 2002
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The effect of IGF-I occurred within an hour, before any detectable increase in cell proliferation, and the activation of CAT expression in response to IGF-I or EGF was blocked by U 0126 ... In stromal cells, the fact that U 0126 blocked the CAT responses to IGF-I and EGF indicates the involvement of a MAP kinase
Yasumoto et al., J Virol 1991
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This restricted LCR region had significant influence on HPV-16-homologous promoters in lowering the CAT expression in the presence and absence of EGF Kitabayashi et al., J Biol Chem 1993
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In addition, EGF induces expression of junB/CAT as strongly as does serum, but neither SRE1 nor SRE2 is sufficient for responsiveness to EGF
Zhang et al., J Biol Chem 1997
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A two-base mutation of the ERE completely eliminated its binding activity as well as its EGF inducibility of CAT expression