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Morise et al., Inflammation 1999 : Constitutive and LPS stimulated expression of intercellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule (VCAM)-1 and E-selectin were measured in wild type C57BL/6 and IL-10 deficient mice with no signs of active enterocolitis, using the dual radiolabeled monoclonal antibody technique
Wei et al., Surgery 1999 : DEM significantly inhibited LPS induced E-selectin surface expression and mRNA levels in a dose dependent fashion, with complete inhibition at 250 mumol/L, without affecting cell viability
Charreau et al., Transplantation 2000 : The ability of immunosuppressive drugs, used alone or in combination, to prevent in vitro TNFalpha- and LPS induced expression of E-selectin and interleukin 8 on porcine ECs, as well as their effect on leukocyte-EC interaction, were investigated
Kalden et al., Ann N Y Acad Sci 1999 (Inflammation) : Thus, we investigated the influence of alpha-MSH on the LPS induced expression of the adhesion molecules E-selectin and VCAM-1 on endothelial cells ... RT-PCR analysis showed that alpha-MSH significantly reduced LPS induced expression of VCAM-1 and E-selectin
Cerwinka et al., Shock 2001 (Hypercholesterolemia) : However, hypercholesterolemia enhanced LPS induced expression of P-selectin, E-selectin , and ICAM-1 in several vascular beds, while VCAM-1 expression was unaffected
Darveau et al., Infect Immun 2002 : In addition, P. gingivalis LPS inhibits endothelial cell expression of E-selectin and interleukin 8 (IL-8) induced by other bacteria
Bessa et al., Gastroenterology 2002 (Colonic Neoplasms) : Neither baseline nor LPS induced endothelial ICAM-1, P-, and E-selectin expression in tumors were reduced with respect to nontumor vasculature
Zeuke et al., Cardiovasc Res 2002 (Heart Failure) : FACS analysis showed an LPS induced upregulation of ICAM-1, VCAM, and ELAM-1
Hijiya et al., Pathobiology 2002 : The LPS induced E-selectin expression in HUVEC was significantly inhibited by pretreatment with an anti-TLR4 mAb ... LPS induced E-selectin and IL-6 production by HUVEC only in the presence of human serum, suggesting the involvement of soluble CD14 ... Anti-CD14 mAb strongly inhibited the LPS induced E-selectin and IL-6 production by HUVEC
Subbanagounder et al., Vascul Pharmacol 2002 (Inflammation) : HOOA-PC also inhibited LPS induced expression of E-Selectin , a major adhesion molecule that mediates neutrophil endothelial interactions
Kadl et al., Vascul Pharmacol 2002 (Inflammation) : In contrast, E-selectin was selectively induced by LPS , but not by OxPAPC
Scholzen et al., Endocrinology 2003 (Vasculitis) : In HDMEC, alpha-MSH ( 10 ( -8 ) /10 ( -12 ) M ) profoundly reduced the mRNA and protein expression of E-selectin , vascular CAM (VCAM)-1, and intercellular CAM (ICAM)-1 induced by LPS or TNFalpha as determined by semiquantitative RT-PCR, ELISA, and fluorescence activated cell sorter analysis
Lush et al., Gastroenterology 2003 (Bacterial Infections) : LPS increased vascular E-selectin expression in wild-type mice
Walton et al., Arterioscler Thromb Vasc Biol 2003 : We have previously shown that phospholipid oxidation products of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine ( ox-PAPC ) inhibit lipopolysaccharide (LPS) induced E-selectin expression and neutrophil binding in human aortic endothelial cells ( HAECs )
Zhang et al., Thromb Haemost 2003 : Furthermore, by using specific cell ELISAs we could show that AS-IV decreased the LPS induced expression of E-selectin and VCAM-1 on the surface of HUVECs in a dose and time dependent manner, whereas the expression of ICAM-1 was not affected by AS-IV ... The saponin octyl-D-glucopyranoside had no effect on the LPS induced expression of E-selectin and VCAM-1 excluding an unspecific detergent-like effect of AS-IV
Madan et al., J Ethnopharmacol 2003 (Edema) : Schult ( Gentianaceae ) inhibits LPS induced expression of ICAM-1 and E-selectin on endothelial cells and carageenan induced paw-edema in rats ... Our results demonstrated that treatment of human endothelial cells with the extract down-regulated the LPS induced expression of ICAM-1 and E-selectin
Coats et al., Infect Immun 2003 : Pretreatment of HUVECs with P. gingivalis LPS did not influence the ability of E. coli LPS to stimulate E-selectin mRNA expression
Dixon et al., Clin Exp Immunol 2004 : Intact meningococci induce far higher levels of CD62E than lipopolysaccharide (LPS) alone, whereas LPS is at least as potent as meningococci at inducing both VCAM-1 and ICAM-1 expression
Schabbauer et al., Arterioscler Thromb Vasc Biol 2004 (Disease Models, Animal...) : Inhibition of the PI3K-Akt pathway also strongly enhanced LPS induced cytokine expression and the levels of soluble E-selectin in the plasma, suggesting enhanced activation of both monocytes and endothelial cells
Witzenbichler et al., Circulation 2005 (Pulmonary Edema...) : Furthermore, LPS induced increases in the expression level of vascular cell adhesion molecule-1, intracellular adhesion molecule-1, and E-selectin protein in the lungs were markedly lower in AdhAng1 mice than in control mice
Zhang et al., Zhongguo Zhong Yao Za Zhi 2005 : l-THP ( 250 mg x L ( -1 ) ) markedly attenuated ICAM-1 and E-selectin expression induced by LPS ( P < 0.05 ). l-THP ( 50 mg x L ( -1 ) inhibited E-selectin expression ( P < 0.05 ) but had no effect on ICAM-1 ( P > 0.05 ). l-THP ( 10 mg x L ( -1 ) ) had no effect on expression of both adhesion molecules ... l-THP depresses expression of ICAM-1 and E-selectin induced by LPS , which suggests that I-THP represent a promising candidate to be developed into therapies for the treatment of inflammation
Waldow et al., Nitric Oxide 2006 : The induction of vascular cell adhesion molecule ( VCAM ), intercellular adhesion molecule ( ICAM ) and E-selectin by the cytokines TNFalpha and IL-1beta, and by bacterial lipopolysaccharide (LPS) was reduced by SNAP/Cys preincubation ( 30 min, 1mM ) to less than 10 % of controls
Leeuwenberg et al., J Immunol 1990 : ELAM-1 is normally not expressed by HUVE cells, but its expression can rapidly be induced by TNF, IL-1, or LPS
Inoue et al., Experimental biology and medicine (Maywood, N.J.) 2006 (Brain Ischemia...) : Both DEP components exacerbated lung inflammation, vascular permeability, and the increased fibrinogen and E-selectin levels induced by LPS
Korotaeva et al., Biomedit͡sinskai͡a khimii͡a 2007 (Inflammation) : LPS induced expression of E-selectin on human endothelial cells was inhibited by oxidized phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine, and phosphatidic acids
Huang et al., Am J Physiol Lung Cell Mol Physiol 2007 : DXM and 1400W attenuated the mRNA expression of E-selectin and iNOS induced by the costimulation of reIL-4, reTNF-alpha, and LPS
Singh et al., Phytomedicine 2008 : The major CAMs, viz., intercellular adhesion molecule-1 ( ICAM-1 ), VCAM-1 and E-selectin are expressed on endothelium in response to various cytokines or bacterial LPS
Sanz et al., Br J Pharmacol 2007 : Immunohistochemical analyses revealed that roflumilast prevented LPS induced endothelial P- and E-selectin expression
Westerterp et al., Circulation 2007 (Atherosclerosis...) : In fact, apoCI expression increased the LPS induced atherosclerotic lesion area by 60 % ( P < 0.05 ), concomitant with an increase in LPS induced plasma levels of fibrinogen and E-selectin
Weppler et al., Exp Lung Res 2008 : Epithelial cells in the bilayer reduced expression of E-selectin on the endothelium in response to LPS , but not with TNF-alpha stimulation
Kadl et al., Arthritis Rheum 2009 (Inflammation...) : LPS , but not OxPAPC, induced the expression of adhesion molecules E-selectin , P-selectin, intercellular adhesion molecule 1, and vascular cell adhesion molecule 1
Carlos et al., J Leukoc Biol 1990 : This result implies the presence of a CD18 independent and PMA-insensitive receptor on human monocytes for an E-LAM induced by LPS
Makó et al., Cytometry A 2010 : Moreover, expression of E-selectin , IL-6, and IL-8 was induced most efficiently by IL-1ß, while LPS and TNF-a had less effect, whereas we did not find such a difference in ICAM-1 and MCP-1 expression
Lin et al., Shock 2013 (Acute Lung Injury) : In addition, LPS increased pulmonary tissue wet-to-dry weight ratio and tumor necrosis factor a and interleukin 8 levels in plasma and bronchoalveolar lavage fluid enhanced the expression of E-selectin , intercellular adhesion molecule 1, myeloperoxidase, MMP-2, and MMP-9, whereas it decreased the expression of AQP-1 and AQP-5 in pulmonary tissue, all of which were attenuated by SalB pretreatment
von Asmuth et al., Immunology 1993 : Anti-CD14 Ab inhibited LPS induced interleukin-6 (IL-6) release and E-selectin expression by cultured human umbilical vein endothelial cells ( HUVEC )
Yang et al., J Immunol 1994 (Sarcoma, Kaposi...) : ICAM-1, VCAM-1, and E-selectin were all induced by dsRNA ( poly ( I:C ) ), IL-1 beta, TNF-alpha, and LPS in KS cells
Repo et al., Scand J Immunol 1994 : Alkali treated LPS of Yersinia enterocolitica does not induce expression of E-selectin , ICAM-1 or VCAM-1 on endothelial cells but may mediate antibody- and complement dependent cell injury ... Studies of the mechanism underlying the poor augmentation revealed that neither enzymatically deacylated LPS from Escherichia coli J5 ( J5 dLPS ) nor yersinia LPS-OH stimulated expression of endothelial cell adhesion molecules E-selectin , VCAM-1 and ICAM-1, whereas both intact J5 LPS and yersinia LPS were stimulatory
Ulich et al., Inflammation 1994 (Acute Disease...) : LPS induces E-selectin expression ; anti-E-selectin and soluble E-selectin inhibit acute inflammation
Darveau et al., Infect Immun 1995 (Bacterial Infections...) : In addition, P. gingivalis LPS blocked E-selectin expression by LPS obtained from other bacteria
Huang et al., Inflammation 1995 : Lipopolysaccharide induced E-selectin expression requires continuous presence of LPS and is inhibited by bactericidal/permeability increasing protein ... E-selectin is induced within 1-2 h, peaks at 4-6 h, and gradually returns to basal level by 24 h. rBPI21, a recombinant N-terminal fragment of human bactericidal/permeability increasing protein ( BPI ), inhibited LPS induced E-selectin expression when added at the same time as, and up to 6 h after, LPS
Leeuwenberg et al., Cytokine 1995 : In contrast, both MR2-1 and pAb75 inhibited specifically TNF induced E-selectin and ICAM-1 expression, but not activation by IL-1 or LPS
Sakai et al., Life Sci 1996 : Pretreatment of diclofenac inhibited LPS induced expression of E-selectin , intercellular adhesion molecule-1 ( ICAM-1 ) and vascular cell adhesion molecule-1 ( VCAM-1 ) in HUVEC, determined by flow cytometry and a cellular enzyme linked immunosorbent assay ( cell-ELISA ) ... The inhibitory activity was concentration dependent between 15.6 and 250 micrograms/ml. Diclofenac also inhibited LPS induced increases in E-selectin , ICAM-1 and VCAM-1 mRNAs, indicating that the action of diclofenac is to inhibit synthesis of these molecules
Sakai et al., Inflamm Res 1996 : Pretreatment of SJC13 inhibited LPS induced expression of E-selectin and vascular cell adhesion molecule-1 ( VCAM-1 ), but not intercellular adhesion molecule-1 ( ICAM-1 ), in HUVEC, determined by flow cytometry and cellular enzyme linked immunosorbent assay ( cell-ELISA ) ... The inhibitory activity was concentration dependent between 62.5 and 1,000 micrograms/ml. SJC13 also selectively inhibited LPS induced increases in E-selectin and VCAM-1 mRNAs, indicating that the action of SJC13 is to inhibit synthesis of these molecules
Morandini et al., Am J Physiol 1996 : The stimulatory effects of phorbol 12-myristate 13-acetate and bacterial lipopolysaccharide (LPS) on E-selectin expression were also downregulated by the forskolin-rolipram combination and by SpcAMPS
Eppihimer et al., Circ Res 1996 : LPS also induced a time dependent upregulation of E-selectin , with maximal expression occurring 3 to 5 hours after intraperitoneal administration
Adamson et al., Cell adhesion and communication 1996 : Stimulation of HUVEC with IL-1 alpha, TNF alpha or LPS for between 2 and 6h followed by removal or neutralisation of IL-1 alpha, TNF alpha or LPS and incubation in new media up to 6h resulted in identical levels of E-selectin expression at 6h, as cells which had been continuously stimulated for 6h with IL-1 alpha, TNF alpha or LPS ... These studies suggest that HUVEC can become committed to the induction of E-selectin after removal of the stimulus and that protein tyrosine kinase inhibitors do not effect initial ( 5-30 min ) cytokine or LPS signals which result in E-selectin expression but can inhibit the expression of cytokine/LPS induced E-selectin expression at a step distal to MAP-kinase activation
Rice et al., Anal Biochem 1996 : The effects of IL-1 beta, TNF alpha, LPS , and an LPS conditioned plasma product on E-selectin expression were characterized
Henseleit et al., J Pathol 1996 (Dermatitis, Allergic Contact...) : LPS and tumour necrosis factor-alpha (TNF-alpha), but not interleukin-4 (IL-4) or interferon-gamma (IFN-gamma), induced a transient expression of E-selectin , both when injected in vivo and when added to endothelial cell lines in vitro
Ishizaka et al., Nihon Kyobu Shikkan Gakkai Zasshi 1996 (Acute Disease...) : The LPS induced increases in ICAM-1 and ELAM-1 expression were dose-dependently suppressed by B464
Lo et al., J Immunol 1998 : FACS analysis reveals that LPG treatment blocked the LPS mediated expression of E-selectin , intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 on endothelial cells and monocyte adhesion without altering the integrity of the endothelial monolayer
Boyle et al., Circulation 1998 (Inflammation) : As measured with the use of an enzyme linked immunosorbent assay, TNF-alpha, IL-1, and LPS each induced a significant increase in surface expression of E-selectin in cultured human umbilical vein endothelial cells ( HUVECs ) compared with HUVECs treated with medium alone