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CPOX — IL18
Text-mined interactions from Literome
Moore et al., J Appl Physiol 2001
:
In human cultured airway smooth muscle cells,
interleukin (IL)-1 beta
increases cyclooxygenase (COX)-2 expression and PGE ( 2 ) release, ultimately resulting in decreased beta-adrenergic responsiveness
Oku et al., Hum Reprod 2004
(Endometriosis) :
The
effects of
IL-18 on
cyclooxygenase (COX)-II gene expression were analysed in peritoneal fluid monocytes and endometriotic cells of endometriosis patients
Helmersson et al., Free radical research 2005
(Cardiovascular Diseases...) :
This study investigated the longitudinal association between serum selenium ( s-Se ) and a golden standard indicator of oxidative stress in vivo ( 8-iso-prostaglandin F2alpha, a major F2-isoprostane ), an indicator of
cyclooxygenase (COX) mediated inflammation ( prostaglandin F2alpha ), high sensitive C-reactive protein ( hsCRP ),
interleukin-6 (IL-6) and serum amyloid A protein (SAA) in a follow-up study of 27 years
John et al., Histol Histopathol 2007
(MAP Kinase Signaling System) :
The
effects of
IL-18 on the cartilage-specific matrix protein collagen type II, the cytoskeletal protein vinculin, the cell matrix signal transduction receptor beta-integrin, key signalling proteins of the MAPKinase pathway ( such as SHC ( Sarc Homology Collagen ) and activated MAPKinase [ERK-1/-2 ] ), the pro-inflammatory enzyme
cyclo-oxygenase-2 (COX-2) and the apoptosis marker activated caspase-3 were evaluated by Western blot analysis and immunofluorescence labelling
Dean et al., J Biol Chem 1999
:
We have previously shown that the pyridinyl imidazole SB 203580, which inhibits it, blocks the
interleukin-1 induction of
cyclooxygenase-2 (COX-2) and matrix metalloproteinase 1 and 3 mRNAs in fibroblasts