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TNF — TNFSF12

Text-mined interactions from Literome

Schneider et al., Eur J Immunol 1999 : Here we show that soluble TWEAK is sufficient to induce apoptosis in Kym-1 cells within 18 h. TWEAK induced apoptosis is indirect and is mediated by the interaction of endogenous TNF and TNF receptor (TNFR)1, as each TNFR1-Fc, neutralizing TNF-specific antibodies and TNFR1-specific Fab fragments efficiently antagonize cell death induction
Zimmermann et al., J Allergy Clin Immunol 2011 (Dermatitis, Atopic...) : TWEAK upregulates TNF-a expression in primary keratinocytes, whereas TNF-a did not affect the expression of TWEAK and its receptors
Echeverry et al., Journal of neuroinflammation 2012 (Anoxia...) : We used enzyme linked immunosorbent assay to study the effect of TWEAK on the expression of neuronal TNF-a , Western blot analysis to investigate whether the effect of TWEAK was mediated by activation of mitogen activated protein kinases and immunohistochemical techniques and quantitative real-time polymerase chain reaction analysis to study the effect of TWEAK on apoptotic cell death
Gu et al., PloS one 2013 (Carcinoma...) : In vitro, we demonstrated that TWEAK only inhibited ovarian cancer HO-8910PM cell proliferation in combination with tumor necrosis factor-I± (TNF-I±), whereas either TWEAK or TNF-I± alone did n't affect HO-8910PM cell growth ... TWEAK promoted TNF-I± production in cultured THP-1 macrophages