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QRICH2 — TNF
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Pithon-Curi et al., Cell Biochem Funct 2002
:
The
effect of
glutamine on nitric oxide ( NO ) and
tumour necrosis factor (TNF) production by peritoneal neutrophils, obtained after glycogen administration, cultured in the presence of LPS ( 0.5 microg ml(-1) ) was also examined
Kessel et al., Clin Exp Immunol 2008
(Endotoxemia) :
Our objective was to determine the
effects of
glutamine ( Gln ) on Toll-like receptor 4 (TLR-4), myeloid differentiation factor 88 ( Myd88 ) and tumour necrosis factor
(TNF)-alpha receptor associated factor 6 ( TRAF6 ) expression in intestinal mucosa following LPS endotoxaemia in a rat
Yang et al., Nan Fang Yi Ke Da Xue Xue Bao 2008
(Pancreatitis, Acute Necrotizing) :
[
Effect of
glutamine on serum interleukin-8 and
tumor necrosis factor-alpha levels in patients with severe pancreatitis ]
Zhang et al., Inflammation 2008
(Inflammation) :
As a precursor of GSH,
glutamine could prevent the NF-kappaB activation and
attenuate the release of
TNF-alpha in LPS stimulated AT-II cells and the effect may be mediated via GSH synthesis
Rogero et al., Amino Acids 2010
:
Peritoneal macrophages were pretreated with glutamine ( 0, 0.6, 2 and 10 mM ) before incubation with lipopolysaccharide (LPS), and the
effects of
glutamine on the production of
tumor necrosis factor-alpha and on the expression and activity of proteins involved in the NF-kappaB signaling pathway were studied by an enzyme linked immuno-sorbent assay, Western blotting, and an electrophoretic mobility shift assay
da Silva Lima et al., Eur J Nutr 2013
(Disease Models, Animal...) :
Further,
glutamine has a dose dependent effect on the activation of macrophages, in both groups, when stimulated with LPS,
inducing a decrease in
TNF-a and IL-1a production and negatively modulating the NF-?B signalling pathway
Peng et al., Eur J Pharmacol 2013
(Acute Kidney Injury) :
Quercetin also abrogated
glutamine 's beneficial
effects on renal
TNF-a , chemokines, and neutrophil infiltration
Fischer et al., Ann Surg 1996
:
The authors studied the
effects of interleukin-6 (IL-6) and
tumor necrosis factor-alpha (TNF-alpha) on
glutamine and alanine transport in isolated human hepatocytes
Chakrabarti et al., Eur J Biochem 1998
:
Transcriptional
regulation of the rat
glutamine synthetase gene by
tumor necrosis factor-alpha