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MAP3K8 — MAPK14
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Channavajhala et al., J Biol Chem 2003
(MAP Kinase Signaling System) :
Although KSR is a positive regulator of the Ras/mitogen activated protein ( MAP ) kinase pathway, the role of KSR in
Cot mediated
MAPK activation has not been identified
Korchnak et al., Cell Signal 2009
:
Mixed lineage kinase 3 (MLK3) is a mitogen activated protein kinase kinase kinase (
MAP3K ) that
activates multiple mitogen activated protein kinase (
MAPK ) pathways in response to growth factors, stresses and the pro-inflammatory cytokine, tumor necrosis factor (TNF)
Tsatsanis et al., Oncogene 1998
(Lymphoma, T-Cell) :
Since the activation of NFAT is MAPK dependent these findings suggested that the
activation of
MAPK by
Tpl-2 is either independent or only partially dependent on MEK1 and MEK2