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GSR — IL12A

Text-mined interactions from Literome

Komatsu et al., Free radical research 2003 : It was found that the glutathione reductase inhibitor, 1,3-bis ( 2-chloroethyl ) -1-nitrosourea, markedly augmented LPS induced IL-12p40 production particularly when it was added for 24 h before LPS stimulation, whereas the glutathione-synthesis inhibitor, L-buthionine- ( S, R ) -sulfoximine, suppressed IL-12p40 production
Motegi et al., J Leukoc Biol 2008 (Bacterial Infections...) : We previously proposed that mouse CD8 ( + ) CD122 ( + ) T cells and human CD57 ( + ) T cells, which increase with age and exhibit potent IFN-gamma production, represent a double edged sword as they play critical roles in host defense and the lethal IL-12/LPS induced generalized Shwartzman reaction (GSR)