◀ Back to PTGS2

ATP4A — PTGS2

Text-mined interactions from Literome

Berenguer et al., Eur J Pharmacol 2002 (Chronic Disease...) : The animals were treated orally for 8 and 15 days, twice daily, with the conventional NSAID, piroxicam ( 0.35 mg/kg ), the non-narcotic analgesic, metamizol ( 33 mg/kg ), the selective cyclooxygenase-2 inhibitor, celecoxib ( 1.8 mg/kg ) and the proton pump inhibitor , omeprazole ( 0.35 mg/kg )
Vonkeman et al., Arthritis Res Ther 2007 (Peptic Ulcer...) : Concomitant proton-pump inhibitors ( but not selective COX-2 inhibitors ) were associated with a reduced risk for NSAID ulcer complications ( the adjusted odds ratio 0.33 ; 95 % confidence interval 0.17 to 0.67 ; p = 0.002 )
Nandi et al., Clin Exp Pharmacol Physiol 2009 : 1. In the present study, we evaluated the role of cyclo-oxygenase (COX)-1 and COX-2 on gastric acid secretion in rabbit isolated parietal cells and gastric glands by examining [ ( 14 ) C ] -aminopyrine uptake, prostaglandin ( PG ) E ( 2 ) synthesis and COX-1, COX-2 and proton pump expression at baseline and after treatment with various concentrations of specific COX-1 ( SC-560 ), COX-2 ( 5,5-dimethyl-3- ( 3-fluorophenyl ) -4- ( 4-methyl-sulphonyl ) phenyl-2 ( 5H ) -furanone ; DFU ) and non-specific COX ( indomethacin ) inhibitors