Spinella et al., J Cardiovasc Pharmacol 2004
(Ovarian Neoplasms) :
In this study we demonstrated that endothelin-1 induced cyclooxygenase-2 and related prostaglandin E2 release were dependent upon the activation of endothelin-A receptor and of multiple mitogen activated protein kinase signal pathways, including extracellular signal regulated kinase 1/2 kinase, p38 mitogen activated protein kinase and the transactivation of the epidermal growth factor receptor
Jin et al., J Korean Med Sci 2010
(Skin Diseases) :
In addition, ETA suppressed the expression of IL-1beta, COX-2 , and MMP-13 induced by UV irradiation