Gene interactions and pathways from curated databases and text-mining

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IL8 — PPARG

Text-mined interactions from Literome

Lappas et al., J Clin Endocrinol Metab 2002 : The aim of this study was to elucidate whether natural [ 15-deoxy-Delta ( 12,14 ) -PGJ ( 2 ) ( 15d-PGJ ( 2 ) ) ] and synthetic ( troglitazone ) PPAR-gamma ligands regulate the secretion of IL-6, IL-8 , and TNF-alpha from human intrauterine tissues
Liu et al., Mol Pharmacol 2003 : In addition, we show that AJA inhibits interleukin-8 promoter activity in a PPARgamma dependent manner, suggesting a link between the anti-inflammatory action of AJA and the activation of PPARgamma
Pawliczak et al., J Biol Chem 2004 : It has been reported that interleukin-8 (IL-8) and cyclooxygenase-2 (COX-2) expression is regulated by peroxisome proliferator activated receptor ( PPAR)-gamma synthetic ligands
Higashihara et al., Redox Rep 2004 : These results suggest that NF-kappaB and PPAR-gamma regulate H/R stimulated IL-8 production in U937 cells
Rajaram et al., J Immunol 2010 : When activated, PPARgamma promotes IL-8 and cyclooxygenase 2 expression, a process modulated by a PPARgamma agonist or antagonist