◀ Back to IL8
IL8 — PPARG
Text-mined interactions from Literome
Lappas et al., J Clin Endocrinol Metab 2002
:
The aim of this study was to elucidate whether natural [ 15-deoxy-Delta ( 12,14 ) -PGJ ( 2 ) ( 15d-PGJ ( 2 ) ) ] and synthetic ( troglitazone )
PPAR-gamma ligands
regulate the secretion of IL-6,
IL-8 , and TNF-alpha from human intrauterine tissues
Liu et al., Mol Pharmacol 2003
:
In addition, we show that AJA inhibits
interleukin-8 promoter activity in a
PPARgamma dependent manner, suggesting a link between the anti-inflammatory action of AJA and the activation of PPARgamma
Pawliczak et al., J Biol Chem 2004
:
It has been reported that
interleukin-8 (IL-8) and cyclooxygenase-2 (COX-2) expression is
regulated by peroxisome proliferator activated receptor (
PPAR)-gamma synthetic ligands
Higashihara et al., Redox Rep 2004
:
These results suggest that NF-kappaB and
PPAR-gamma regulate H/R stimulated
IL-8 production in U937 cells
Rajaram et al., J Immunol 2010
:
When activated,
PPARgamma promotes
IL-8 and cyclooxygenase 2 expression, a process modulated by a PPARgamma agonist or antagonist