◀ Back to TP53
SERPINF1 — TP53
Text-mined interactions from Literome
Sasaki et al., Oncogene 2005
(Colorectal Neoplasms...) :
We discovered that the expression of
pigment epithelium derived factor (PEDF) was specifically
induced by either p63 or p73, but not by
p53
Ho et al., Cardiovasc Res 2007
:
PEDF sequentially
induced PPARgamma and
p53 expression as observed in immunoblotting and immunofluoresence assays ...
PEDF also
increased the transcriptional activity of PPARgamma as evident from electromobility shift assays, and
p53 as determined by the phosphorylation and acetylation of p53 and the induction of Bax ... The
induction of
p53 by
PEDF was abolished by either PPARgamma antagonist or PPARgamma siRNA ... Our observations indicate that
PEDF induces HUVECs apoptosis through the sequential induction of PPARgamma and
p53 overexpression