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IFNG — MICA
Text-mined interactions from Literome
Tieng et al., Proc Natl Acad Sci U S A 2002
(Crohn Disease) :
MICA induction on epithelial cells
triggered IFN-gamma release by the NKG2D expressing natural killer cell line NKL
Girlanda et al., Cancer Res 2005
(Multiple Myeloma...) :
MICA expressed by myeloma cell lines
contributed to killing and
IFN-gamma production by Vgamma9/Vdelta2 cells only upon pamidronate treatment, suggesting a dual interaction between Vgamma9/Vdelta2 lymphocytes and multiple myeloma plasma cells involving both TCR triggering and NKG2D mediated signals
Yadav et al., J Immunol 2009
:
One of these miRNAs ( miR-520b ) was
induced by
IFN-gamma , leading to a reduction in
MICA surface protein levels
Gong et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2009
:
Soluble
MICA inhibited the cytotoxicity of NK cells and
down-regulated the secretion of
IFN-gamma , but it showed no effects on the proliferation and apoptosis of freshly isolated peripheral NK cells
Poggi et al., Curr Med Chem 2009
(Acute Disease...) :
Both Vdelta1 and Vdelta2 T cells can produce
interferon-gamma in
response to
MIC-A ( + ) cells or non-peptide antigens, respectively
Liu et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2010
(Lung Neoplasms) :
RT-PCR and MTT methods were used to detect the effect on
MICA mRNA expression
induced by
IFN-gamma in the edited A549 cells and the change of CIK killing sensitivity to A549 cells, respectively ...
IFN-gamma could significantly
increase MICA mRNA expression in the edited A549 cells and improve CIK cell cytotoxicity