Gene interactions and pathways from curated databases and text-mining

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IFNG — MICA

Text-mined interactions from Literome

Tieng et al., Proc Natl Acad Sci U S A 2002 (Crohn Disease) : MICA induction on epithelial cells triggered IFN-gamma release by the NKG2D expressing natural killer cell line NKL
Girlanda et al., Cancer Res 2005 (Multiple Myeloma...) : MICA expressed by myeloma cell lines contributed to killing and IFN-gamma production by Vgamma9/Vdelta2 cells only upon pamidronate treatment, suggesting a dual interaction between Vgamma9/Vdelta2 lymphocytes and multiple myeloma plasma cells involving both TCR triggering and NKG2D mediated signals
Yadav et al., J Immunol 2009 : One of these miRNAs ( miR-520b ) was induced by IFN-gamma , leading to a reduction in MICA surface protein levels
Gong et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2009 : Soluble MICA inhibited the cytotoxicity of NK cells and down-regulated the secretion of IFN-gamma , but it showed no effects on the proliferation and apoptosis of freshly isolated peripheral NK cells
Poggi et al., Curr Med Chem 2009 (Acute Disease...) : Both Vdelta1 and Vdelta2 T cells can produce interferon-gamma in response to MIC-A ( + ) cells or non-peptide antigens, respectively
Liu et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2010 (Lung Neoplasms) : RT-PCR and MTT methods were used to detect the effect on MICA mRNA expression induced by IFN-gamma in the edited A549 cells and the change of CIK killing sensitivity to A549 cells, respectively ... IFN-gamma could significantly increase MICA mRNA expression in the edited A549 cells and improve CIK cell cytotoxicity