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F2R — POLDIP2
Text-mined interactions from Literome
Syeda et al., J Biol Chem 2006
:
PAR-1 and PAR-2 stimulation rapidly
activated both ERK1/2 and
p38MAPK , and pharmacological blockade of MEK with either PD98059 or U0126 or of p38MAPK by SB203580 or SB202190 strongly inhibited thrombin- and SLIGKV induced COX-2 expression and 6-keto-PGF1alpha formation
Rohani et al., BMC immunology 2010
(Periodontitis) :
Our data show the induction of innate immunity by
PAR1 requires both
p38 and ERK MAP kinases, while PAR2 prominently signals via p38