Gene interactions and pathways from curated databases and text-mining

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JUN — MAPK8IP1

Text-mined interactions from Literome

Bonny et al., J Biol Chem 2000 : Reducing IB1 levels in these cells increased phosphorylation of c-Jun and increased the apoptotic rate in presence of IL-1beta
Fan et al., J Biol Chem 2000 (MAP Kinase Signaling System) : Stable expression of the JNK scaffold protein JIP-1 blocked vinblastine induced phosphorylation of c-Jun and ATF-2, but did not affect Bcl-2/Bcl-X ( L ) phosphorylation, confirming a bifurcation in JNK signaling involving both nuclear and non-nuclear substrates
Ikezoe et al., Br J Cancer 2004 (Prostatic Neoplasms) : Thus, TPA stimulated c-Jun through JNK, and JIP-1 effectively blocked JNK
Morel et al., Mol Cell Biol 2010 (Fatty Liver...) : Requirement of JIP1 mediated c-Jun N-terminal kinase activation for obesity induced insulin resistance
Mooser et al., Genomics 1999 : Islet-brain 1 (IB1), a regulator of the pancreatic beta-cell function in the rat, is homologous to JIP-1 , a murine inhibitor of c-Jun amino-terminal kinase (JNK)