Turley et al., Am J Physiol Gastrointest Liver Physiol 2010
:
However, none of these studies has specifically addressed how ACAT2 deficiency impacts the relative proportions of esterified and unesterified cholesterol ( UC ) in the enterocyte and whether the concurrent loss of ABCA1 might result in a marked buildup of UC
Kolouchova et al., J Gastroenterol Hepatol 2011
(Cholestasis...) :
The change was accompanied by the reduced liver expression of Hmg-CoA reductase, LDL receptor, and Acat2 , and induced the expression of Abca1 and Mdr2