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MSH2 — MSH3

Pathways - manually collected, often from reviews:

• Reactome Reaction: MSH2 → MSH3 (reaction) Zhang et al., Cell 2005, Kadyrov et al., Cell 2006
• Reactome Reaction: MSH2 → MSH3 (direct_complex)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind_translation Interaction: MSH3 — MSH2 (affinity chromatography technology) Guerrette et al., Mol Cell Biol 1998*
• IRef Biogrid Interaction: MSH3 — MSH2 (direct interaction, pull down) Bocker et al., Cancer Res 1999
• IRef Biogrid Interaction: MSH3 — MSH2 (direct interaction, pull down) Acharya et al., Proc Natl Acad Sci U S A 1996*
• IRef Biogrid Interaction: MSH3 — MSH2 (physical association, affinity chromatography technology) Palombo et al., Curr Biol 1996*
• IRef Biogrid Interaction: MSH3 — MSH2 (colocalization, biochemical) Havugimana et al., Cell 2012
• IRef Biogrid Interaction: MSH3 — MSH2 (direct interaction, pull down) Owen et al., Nature structural & molecular biology 2009*
• IRef Biogrid Interaction: MSH3 — MSH2 (physical association, affinity chromatography technology) Wang et al., Proc Natl Acad Sci U S A 2003*
• IRef Biogrid Interaction: MSH3 — MSH2 (direct interaction, pull down) Guerrette et al., Mol Cell Biol 1998*
• MIPS CORUM MSH2-MSH3 complex: MSH2-MSH3 complex complex (MSH2-MSH3) Acharya et al., Proc Natl Acad Sci U S A 1996*
• MIPS CORUM MutS-beta complex: MutS-beta complex complex (MSH2-MSH3) Palombo et al., Curr Biol 1996*
• IRef Corum Interaction: MSH3 — MSH2 (association, anti bait coimmunoprecipitation) Acharya et al., Proc Natl Acad Sci U S A 1996*
• IRef Corum Interaction: MSH3 — MSH2 (association, protein cross-linking with a bifunctional reagent) Acharya et al., Proc Natl Acad Sci U S A 1996*
• IRef Corum Interaction: MSH3 — MSH2 (association, coimmunoprecipitation) Palombo et al., Curr Biol 1996*
• IRef Dip Interaction: MSH3 — MSH2 (direct interaction, molecular sieving) Gupta et al., Nature structural & molecular biology 2012*
• IRef Dip Interaction: MSH3 — MSH2 (direct interaction, x-ray crystallography) Gupta et al., Nature structural & molecular biology 2012*
• IRef Dip Interaction: MSH3 — MSH2 (direct interaction, ion exchange chromatography) Gupta et al., Nature structural & molecular biology 2012*
• IRef Dip Interaction: MSH3 — MSH2 (direct interaction, cosedimentation in solution) Owen et al., Nature structural & molecular biology 2005*
• IRef Dip Interaction: MSH3 — MSH2 (direct interaction, ion exchange chromatography) Owen et al., Nature structural & molecular biology 2009*
• IRef Dip Interaction: MSH3 — MSH2 (direct interaction, pull down) Gupta et al., Nature structural & molecular biology 2012*
• IRef Hprd Interaction: MSH2 — MSH3 (in vivo) Acharya et al., Proc Natl Acad Sci U S A 1996*, Guerrette et al., Mol Cell Biol 1998*
• IRef Hprd Interaction: MSH2 — MSH3 (in vitro) Acharya et al., Proc Natl Acad Sci U S A 1996*, Guerrette et al., Mol Cell Biol 1998*
• IRef Hprd Interaction: MSH2 — MSH3 (two hybrid) Acharya et al., Proc Natl Acad Sci U S A 1996*, Guerrette et al., Mol Cell Biol 1998*
• IRef Intact Interaction: Complex of 26 proteins (association, anti tag coimmunoprecipitation) Svendsen et al., Cell 2009
• IRef Intact Interaction: Complex of 222 proteins (association, tandem affinity purification) Koch et al., Cell cycle (Georgetown, Tex.) 2007
• IRef Intact Interaction: MSH3 — MSH2 (physical association, pull down) Guerrette et al., Mol Cell Biol 1998*
• IRef Ophid Interaction: MSH3 — MSH2 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: MSH3 — MSH2 (aggregation, confirmational text mining) Acharya et al., Proc Natl Acad Sci U S A 1996*

Text-mined interactions from Literome

Reenan et al., Genetics 1992 : Evidence presented in this and a companion study suggest that MSH1 is involved in repair of mitochondrial DNA and that MSH2 is involved in nuclear DNA repair
Saydam et al., Nucleic Acids Res 2007 : MutSalpha and MutSbeta can strongly stimulate the helicase activity of WRN specifically on forked DNA structures with a 3'-single stranded arm
Aarts et al., Methods Mol Biol 2009 : We have developed strategies to circumvent this problem based on findings that the central MMR protein MSH2 acts in two different mismatch recognition complexes : MSH2/MSH6 , which mainly recognizes base substitutions ; and MSH2/MSH3, which has more affinity for larger loops