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BDNF — GABRG2

Text-mined interactions from Literome

Ericson et al., J Neurosci Res 2003 (Alcohol-Induced Disorders, Nervous System) : BDNF increased the expression of the GABA(A) receptor alpha6 subunit, whereas ethanol had no effect, in chronically treated granule cell cultures
Lund et al., Science signaling 2008 (Epilepsy) : BDNF selectively regulates GABAA receptor transcription by activation of the JAK/STAT pathway
Ihara et al., Neuropharmacology 2012 : Moreover, GABA(A) receptor activation or a blockade of Ca ( 2+ ) influx even after starting the incubation with DM reduced the elevated activity of Bdnf-pIV
Huang et al., Exp Neurol 2012 (Synaptic Transmission) : However, in the absence of KCC2 activity, BDNF directly potentiated rather than inhibited GABA(A) receptor , which was reflected by an increase in the amplitude of outward IPSCs ... The effects of BDNF on both GABA(A) receptor and KCC2 were dependent on TrkB and also activation of cyclin dependent kinase 5 (Cdk5)
Huang et al., Cerebellum 2013 : Under these conditions in which KCC2 activity is reduced, BDNF augments evoked GABA-A currents suggesting a direct facilitatory effect of BDNF on GABA-A receptor
Thompson et al., Brain Res Mol Brain Res 1998 : Decreased expression of GABAA receptor alpha6 and beta3 subunits in stargazer mutant mice : a possible role for brain derived neurotrophic factor in the regulation of cerebellar GABAA receptor expression ?