◀ Back to TNF
ETS2 — TNF
Text-mined interactions from Literome
Wei et al., J Immunol 2004
(Inflammation) :
Ets2 phosphorylation was
required for persistent activation of
TNF-alpha following LPS stimulation of bone marrow derived macrophages
Zhang et al., Arthritis Rheum 2005
(Arthritis, Experimental...) :
Bcl-xL or Ets-2 overexpression protected osteoclasts from ALN induced apoptosis, and
TNF stimulated Bcl-xL and
Ets-2 expression in osteoclasts
Lee et al., Infect Immun 2005
:
Our data indicate that the increased
Ets/Elk and NF-kappaB promoter activities associated with M. smegmatis infected macrophages are
responsible , at least in part, for the increased
TNF-alpha and NOS2 production observed in these infected cells and that ERK1/2 is required for Ets/Elk activity and full TNF-alpha production
Sangiovanni et al., PloS one 2013
:
In vitro,
ETs inhibited
TNF-a induced NF-kB driven transcription ( IC50 : 0.67-1.73 µg/mL ) and reduced TNF-a induced NF-kB nuclear translocation ( 57 % -67 % at 2 µg/mL )