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FGB — RELA
Text-mined interactions from Literome
Guo et al., Thromb Haemost 2004
(Inflammation) :
From our findings, we conclude that
fibrinogen regulates
NF-kappaB activation and expression of inflammatory chemokines in endothelial cells and may be involved in mediating inflammatory processes
Malaver et al., Journal of thrombosis and haemostasis : JTH 2009
:
Two specific unrelated inhibitors of
NF-kappaB activation, BAY 11-7082 and Ro 106-9920,
reduced PAC-1 and
fibrinogen binding to integrin alpha ( IIb ) beta3 and restricted platelet spreading on immobilized fibrinogen
Sitrin et al., J Immunol 1998
(Leukemia, Monocytic, Acute) :
Mononuclear phagocytes are exposed to fibrinous provisional matrix throughout migration into inflammatory foci, so this study was undertaken to determine whether
fibrinogen triggers activation of
NF-kappa B transcription factors ...
NF-kappa B activation, minimal in unstimulated cells, was substantially
up-regulated by
fibrinogen ... Blocking mAbs against CD18 and CD11b abrogated
fibrinogen induced
NF-kappa B activation